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Table 2 Psychopathology and socioeconomic-, psychosocial-, and perceived stress of the extreme group mothers (all data: mean ± SD or percentage)

From: New-born females show higher stress- and genotype-independent methylation of SLC6A4 than males

Variable

High prenatal ELS (n = 45)

Low prenatal ELS (n = 45)

p value

Maternal psychopathology

   

EPDS Score1

12.33 ± 4.70

1.27 ± 1.45

0.000

STAI-S Score1

51.72 ± 8.05

27.41 ± 3.87

0.000

STAI-T Score1

47.93 ± 8.41

28.04 ± 3.58

0.000

ASQ Score1

4.11 ± 2.14

0.53 ± 0.72

0.000

M.I.N.I. Diagnosis2

   

   None

51.1%

91.1%

0.004

   Depressive disorder

40%

6.7%

0.015

   Anxiety disorder

8.9%

2.2%

ns

Current psychiatric disorder2

   

   None

62.2%

97.8%

0.005

   Depressive disorder

26.7%

0%

0.015

   Anxiety disorder

11%

2.2%

ns

Perceived stress

   

PSS Score1

30.84 ± 5.64

12.84 ± 4.1

0.000

PDQ Score1

19.95 ± 7.56

5.95 ± 2.95

0.000

Socioeconomic and psychosocial stress

   

LES-negative events Score1

6.75 ± 4.39

1.80 ± 1.29

0.010

Soz-U Score1

39.58 ± 3.85

51.89 ± 4.32

0.000

Living without a partner2

20%

0%

0.004

Encouragement (Partner)2

73.3%

100%

ns

Separation(s) in the last year2

24.4%

2.2%

0.002

Daily arguments2

11.1%

2.2%

ns

Physical conflicts within the preceding 12 months2

33.3%

2.2%

0.003

Composition of household > one person/room2

40.5%

0%

0.001

No academic qualification2

4.4%

2.2%

0.050

No professional education2

17.7%

2.2%

0.043

Monthly income per household ≤ 1,750 Euro2

42.2%

0%

0.001

Debt2

24.4%

2.2%

0.002

  1. SD = standard deviation; ns = not significant. 1The first eight main variables of the principal component analysis (PCA), 2The twelve prenatal stressors used to generate the adversity score as the ninth main variable of the PCA.