From: New-born females show higher stress- and genotype-independent methylation of SLC6A4 than males
Variable | High prenatal ELS (n = 45) | Low prenatal ELS (n = 45) | p value |
---|---|---|---|
Maternal psychopathology | Â | Â | Â |
EPDS Score1 | 12.33 ± 4.70 | 1.27 ± 1.45 | 0.000 |
STAI-S Score1 | 51.72 ± 8.05 | 27.41 ± 3.87 | 0.000 |
STAI-T Score1 | 47.93 ± 8.41 | 28.04 ± 3.58 | 0.000 |
ASQ Score1 | 4.11 ± 2.14 | 0.53 ± 0.72 | 0.000 |
M.I.N.I. Diagnosis2 | Â | Â | Â |
   None | 51.1% | 91.1% | 0.004 |
   Depressive disorder | 40% | 6.7% | 0.015 |
   Anxiety disorder | 8.9% | 2.2% | ns |
Current psychiatric disorder2 | Â | Â | Â |
   None | 62.2% | 97.8% | 0.005 |
   Depressive disorder | 26.7% | 0% | 0.015 |
   Anxiety disorder | 11% | 2.2% | ns |
Perceived stress | Â | Â | Â |
PSS Score1 | 30.84 ± 5.64 | 12.84 ± 4.1 | 0.000 |
PDQ Score1 | 19.95 ± 7.56 | 5.95 ± 2.95 | 0.000 |
Socioeconomic and psychosocial stress | Â | Â | Â |
LES-negative events Score1 | 6.75 ± 4.39 | 1.80 ± 1.29 | 0.010 |
Soz-U Score1 | 39.58 ± 3.85 | 51.89 ± 4.32 | 0.000 |
Living without a partner2 | 20% | 0% | 0.004 |
Encouragement (Partner)2 | 73.3% | 100% | ns |
Separation(s) in the last year2 | 24.4% | 2.2% | 0.002 |
Daily arguments2 | 11.1% | 2.2% | ns |
Physical conflicts within the preceding 12Â months2 | 33.3% | 2.2% | 0.003 |
Composition of household > one person/room2 | 40.5% | 0% | 0.001 |
No academic qualification2 | 4.4% | 2.2% | 0.050 |
No professional education2 | 17.7% | 2.2% | 0.043 |
Monthly income per household ≤ 1,750 Euro2 | 42.2% | 0% | 0.001 |
Debt2 | 24.4% | 2.2% | 0.002 |