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Table 2 Baseline use of psychotropic medications across samples of the three published randomized controlled trials of DBT-A for suicidal and self-harming adolescents with borderline features

From: Psychotropic medication use among adolescents participating in three randomized trials of DBT

Drug class

US sample

 

Oslo sample

 

Barcelona sample

All participants

(N = 173)

Participants with MD (n = 142; 82.1%)

 

All participants

(N = 77)

Participants with MD (n = 17; 22.1%)

 

All participants

(N = 35)

Participants with MD (n = 29; 82.9%)

n

%

n

%

 

N

%

n

%

 

n

%

n

%

Any medication with psychiatric use

116

67.1

92

64.8

 

9

11.7

6

35.3

 

30

85.7

25

86.2

Antidepressant (any)

104

60.1

82

57.7

 

5

6.5

2

11.8

 

23

65.7

21

72.4

 SSRI

90

52.0

71

50.0

 

4

5.2

1

5.9

 

19

54.3

-

-

 SNRI

8

4.6

6

4.2

 

0

0

0

0

 

2

5.7

-

-

 Tricyclic

1

0.6

1

0.7

 

0

0

0

0

 

1

2.8

-

-

 Other

22

12.7

18

12.7

 

1

1.3

1

5.9

 

1

2.8

-

-

Anxiolytic (any)

13

7.5

12

8.5

 

0

0

0

0

 

0

0

5

17.2

 Benzodiazepine

10

5.8

10

7.0

 

0

0

0

0

 

5

14.3

-

-

Antipsychotic

38

22.0

30

21.1

 

1

1.3

1

5.9

 

26

74.2

21

72.4

Mood stabilizer a

28

16.2

24

16.9

 

0

0

0

0

 

5

14.2

4

13.8

CNS Stimulant

17

9.8

13

9.2

 

1

1.3

1

5.9

 

5

14.2

5

17.2

Alpha adrenergic

5

2.9

4

2.8

 

0

0

0

0

 

0

0

-

-

Antihistamine

8

4.6

8

5.6

 

2

2.6

2

11.8

 

0

0

-

-

Other b

3

1.7

2

1.4

 

1

1.3

0

0

 

1

2.8

1

3.4

Total number of medications (mean, SD)

1.44

1.51

1.44

1.56

 

0.13

0.38

0.16

0.36

 

1.8

1.13

-

-

  1. Notes: MD = major depression; SSRI = selective serotonin reuptake inhibitors; SNRI = serotonin and norepinephrine reuptake inhibitors; a the category ‘Mood stabilizer’ includes lithium and/or anticonvulsant; b other medications include anticholinergic, melatonin, beta blocker or any other medication used for psychiatric purpose. “- " denotes non-available information