How changes in depression severity and borderline personality disorder intensity are linked – a cohort study of depressed patients with and without borderline personality disorder

Table 1 Demographic and clinical characteristics at baseline and follow-up

Sample		MDD (n = 39)		MDE/BD (n = 33)		MDE/BPD (n = 23)		Total sample (n = 95)
Sample		mean / n	sd / %	mean / n	sd / %	mean / n	sd / %	mean / n	sd / %	p
Age		31.41	10.29	32.79	9.62	27.98	7.10	31.06	9.46	0.167
Sex	Female	21	53.8%	25	75.8%	16	69.6%	62	65.3%	0.168
Sex	Male	18	46.2%	8	24.2%	7	30.4%	33	34.7%
BPD		0	0.0%	2	6.1%	23	100.0%	25	26.3%	< 0.001
Bipolar		0	0.0%	33	100.0%	6	26.1%	39	41.1%	< 0.001
	Type I	0	0.0%	8	24.2%	0	0.0%	8	8.4%
	Type II	0	0.0%	25	75.8%	6	26.1%	31	33.7%
MDE features	Melancholic	12	30.8%	12	36.4%	10	43.5%	34	35.8%	0.585
	Atypical	9	23.1%	3	9.1%	6	26.1%	18	18.9%	0.196
Baseline	MADRS	23.62	5.98	22.21	7.05	21.52	6.35	22.62	6.45	0.426
	BDI II	27.45	9.91	30.44	11.78	32.94	9.54	29.88	10.63	0.215
	OASIS	11.69	3.33	12.85	3.73	12.22	5.08	12.22	3.94	0.467
	BPDSI	14.81	7.33	16.65	6.75	25.60	8.42	17.48	8.29	< 0.001
Follow-up	MADRS	15.43	9.71	12.96	12.00	16.50	4.77	14.79	9.86	0.455
	BDI II	19.32	12.11	19.04	16.58	26.27	10.85	20.54	13.72	0.201
	OASIS	9.16	4.48	8.44	5.33	10.40	4.42	9.15	4.76	0.499
	BPDSI	11.61	8.33	11.88	7.13	19.03	7.85	13.17	8.28	0.005
Correlations	MADRS	0.48		0.32		0.21		0.36
	BDI II	0.45		0.68		0.39		0.53
	OASIS	0.44		0.52		0.55		0.47
	BPDSI	0.66		0.48		0.63		0.69

Notes Correlations are between baseline and follow-up scores. MDD = Major depressive disorder, MDE = Major depressive episode, BD = Bipolar disorder, BPD = Borderline personality disorder, MADRS = Montgomery Åsberg Depression rating scale, BDI II = Beck depression inventory II, OASIS = Overall anxiety severity and impairment scale, BPDSI = BPD severity index. p refers to Anova or Fisher’s exact Χ² testing of intra-subcohort differences

ISSN: 2051-6673