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Table 3 Effect of treatment on weight, depressive symptoms, general psychopathology, psychosocial functioning, and eating disorder symptoms in inpatients with AN and AN+BPD: results of the longitudinal multilevel mixed effects models

From: Impact of comorbid borderline personality disorder on the outcome of inpatient treatment for anorexia nervosa: a retrospective chart review

Outcome

 

AN

 

AN+BPD

N

M pre (95% CI)

M post (95% CI)

p (within-group)

d (95% CI)

N

M pre (95% CI)

M post (95% CI)

p (within-group

d (95% CI)

BMI

1092

14.50 (14.39; 14.61)

17.09 (16.95; 17. 22)

<.001

1.40 (1.31; 1.48)

68

14.99 (14.56; 15.42)

17.18 (16.66; 17.70)

<.001

1.08 (0.77; 1.39)

BSI DEP

887

69.27 (68.60; 69.94)

60.73 (59.90; 61.56)

<.001

0.79 (0.70; 0.87)

54

75.50 (73.87; 77.13)

67.91 (64.61; 71.21)

<.001

0.69 (0.33; 1.03)

BSI GSI

887

71.87 (71.18; 72.56)

61.23 (60.30; 62.16)

<.001

0.95 (0.86; 1.03)

54

77.24 (75.72; 78.76)

70.64 (67.43; 73.85)

<.001

0.65 (0.30; 0.99)

GAF

530

40.12 (39.09; 41.15)

54.46 (53.07; 55.85)

<.001

0.98 (0.87; 1.08)

34

37.32 (33.35; 41.29)

44.53 (39.47; 49.59)

.008

0.48 (0.13; 0.84)

EDI-2 TO

882

0.94 (0.91; 0.97)

0.60 (0.57; 0.63)

<.001

0.96 (0.87; 1.04)

53

1.35 (1.24; 1.46)

1.01 (0.88; 1.14)

<.001

0.99 (0.59; 1.37)

EDI-2 DT

882

1.49 (1.43; 1.55)

0.74 (0.68; 0.80)

<.001

0.95 (0.86; 1.04)

53

1.82 (1.60; 2.04)

1.33 (1.07; 1.59)

<.001

0.80 (0.43; 1.16)

EDI-2 BU

882

0.40 (0.36; 0.44)

0.07 (0.05; 0.09)

<.001

0.51 (0.43; 0.58)

53

0.73 (0.49; 0.97)

0.23 (0.08; 0.38)

<.001

0.71 (0.35; 1.07)

EDI-2 BD

881

1.58 (1.53; 1.63)

1.23 (1.17; 1.29)

<.001

0.53 (0.45; 0.60)

53

1.98 (1.80; 2.19)

1.89 (1.65; 2.11)

.161

0.25 (−0.08; 0.57)

EDI-2 IN

882

1.04 (0.99; 1.09)

0.64 (0.60; 0.68)

<.001

0.66 (0.58; 0.74)

53

1.56 (1.41; 1.77)

1.11 (0.88; 1.34)

<.001

0.77 (0.41; 1.13)

EDI-2 PE

882

1.19 (1.14; 1.24)

0.91 (0.86; 0.96)

<.001

0.50 (0.43; 0.58)

53

1.24 (1.04; 1.44)

1.07 (0.84; 1.30)

.027

0.37 (0.04; 0.70)

EDI-2 ID

882

0.79 (0.75; 0.83)

0.54 (0.50; 0.58)

<.001

0.47 (0.39; 0.54)

53

1.31 (1.13; 1.49)

0.85 (0.67; 1.03)

<.001

0.84 (0.47; 1.21)

EDI-2 IA

882

0.94 (0.90; 0.98)

0.51 (0.47; 0.55)

<.001

0.74 (0.66; 0.82)

53

1.42 (1.25; 1.59)

1.09 (0.90; 1.28)

.001

0.64 (0.29; 0.99)

EDI-2 MF

882

0.91 (0.87; 0.95)

0.66 (0.62; 0.70)

<.001

0.46 (0.39; 0.54)

53

1.26 (1.07; 1.45)

0.82 (0.67; 0.97)

<.001

0.48 (0.14; 0.81)

EDI-2 AS

880

0.83 (0.79; 0.87)

0.54 (0.50; 0.58)

<.001

0.56 (0.48; 0.64)

53

1.30 (1.11; 1.49)

0.96 (0.78; 1.14)

<.001

0.64 (0.29; 0.99)

EDI-2 IR

880

0.41 (0.38; 0.44)

0.24 (0.22; 0.26)

<.001

0.48 (0.40; 0.55)

53

0.83 (0.69; 0.97)

0.63 (0.50; 0.76)

.003

0.46 (0.12; 0.79)

EDI-2 SI

880

0.93 (0.89; 0.97)

0.64 (0.60; 0.68)

<.001

0.60 (0.52; 0.68)

53

1.36 (1.20; 1.52)

1.00 (0.82; 1.18)

<.001

0.62 (0.02; 1.07)

  1. Note. Significant Group x Time Interactions are boldface. AN anorexia nervosa, AN+BPD anorexia nervosa with comorbid Borderline personality disorder, M = estimated marginal mean, 95% CI 95% confidence interval, d = Cohen’s d (calculated with the standard deviation of the pre-treatment values), BMI body mass index, BSI DEP = T-score for the depression scale of the Brief Symptom Inventory, BSI GSI = T-score for the global severity index of the Brief Symptom Inventory, GAF Global Assessment of Functioning. Abbreviations for the Eating Disorder Inventory 2 (EDI-2) scales: TO total, DT drive for thinness, BU bulimia, BD body dissatisfaction, IN ineffectiveness, PE perfectionism, ID interpersonal distrust, IA interoceptive awareness, MF maturity fears, AS asceticism, IR impulse regulation, SI social insecurity