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Table 1 Summary of Studies Included

From: Smartphone applications targeting borderline personality disorder symptoms: a systematic review and meta-analysis

Study

App Name and Description

Control Condition

Len-gth (wks)

N,

% male

% with BPD

Study Inclusion Criteria

Outcomes

Drop-outc

Suicide and Self-Harm Applications

 [18]

TecTec.a Positive stimuli are paired with self, and self-harm related stimuli to aversive stimuli in a gamified format

Gamified format with stimuli pairing, but only with neutral stimuli (RCT)

4

31, 19.3%

NR

Community adults with active NSSI

• ↓ in all self-injurious thoughts and behaviors (SITB) except SI in app group vs. control

• ↓ in self-cutting episodes (32–40%), suicide plans (21–59%), and suicidal behaviors (33–77%)

24.4% (10)

 [18]

40, 26.0%

NR

28.6% (16)

 [18]

33, 41.1%

NR

47.6% (30)

 [40]

BeyondNow. Personalized safety plan, including contacts and emergency services + Treatment as usual

None

~ 10.42

36, 33.3%

22.3%

Adults with elevated suicide risk in mental health treatment

• ↓ severity and intensity of SI

• ↑ suicide-related coping

38.9% (14)

 [47]

LifeApp’tite. Psychoeducation on suicidal thoughts; symptom monitoring; safety plan; digital hope kit; list of self-help skills + Treatment as usual

Treatment as usual in a specialized outpatient suicide prevention clinic (RCT)

~ 9.4

60, 33.3%

NR

Adults referred to treatment or evaluation for to suicidal thoughts

• ↓ in suicide risk in app group < control (only at trend level at 4-month follow up)

• No between-group differences in depression

56.7% (34)

 [49]

BackUp.a Hope box (see VHB); coping cards; tools to recognize warning signs, use coping strategies, and reach out to others

None

1

21, 23.9%

NR

Adults with suicidal thoughts as measured by BSS

• Non-significant ↓ in SI

4.76% (1)

Emotion Regulation Applications

 [38]

RELAX. Tracks anger frequency, intensity, and cues; personalized anger management exercises + Anger management training group

Twice-weekly anger management training outpatient group alone (RCT)

6

28, 100%

NR

Adult armed forces veterans with high levels of STAXI-measured anger

• No differences between app group and control

• ↓ anger severity and PTSD in both groups

10.7% (3)

 [41]

Headspace. Brief mindfulness meditation exercises + acute state hospital treatment.

None

1

12, 83%

NR

Adults with schizophrenia or bipolar disorder and history of aggression or violence.

• No change in state or trait anger

16.7% (2)

 [45]

RELAX. See above + Anger management training group

None

6

4

NR

Adult armed forces veterans participating in anger management group.

• ↓ in anger, PTSD and depression symptoms at post-tx and 3-month follow-up

25.0% (1)

 [17]

EMOTEO. Provides guided mindfulness and distress tolerance exercises depending on stated level of tension + specialized BPD treatment

None

24

16, 0%

100%

Adult women with BPD in specialized treatment

• ↓ aversive tension

NR

Multipurpose (Suicide/Self-Harm, Impulsivity, & Emotion Regulation) Applications

 [7]

VHB. Repository of tools for distraction, relaxation, & stress-coping; fond memories; inspirational quotes + Treatment as usual

Printed materials about coping with suicidality + Treatment as usual (RCT)

12

50, 62.1%

NR

Adult armed forces veterans in treatment with current/past-3-month SI

• Stress coping in VHB > TAU group

• No between-group differences in SI, reasons for living, suicide severity, and perceived stress

13.8% (8)

 [54]

DBT Coach. Suggests emotion-specific opposite action behaviors, tracks emotional intensity and urges to use substances + DBT

None

2

22, 18.2%

100%

Adults with BPD and SUD in current DBT treatment

• ↓ in emotional intensity and urges to use substances

• ↓ in depression and general distress

0% (0)

 [55]

DBT Coach. Same as above but expanded to include most DBT skills, tracks distress and urges to self-harm + DBT

None

36

14, 25%

100%

Adults with BPD and recent history of NSSI and/or suicide attempts

• ↑ app use predicted larger ↓ in NSSI, but not psychopathology, suicidal behavior, or skills use

25% (4)

 [67]

Ibobbly.a Psychoeducation on thoughts, strategies to defuse them and regulate emotions; action plans for value-based goals

Waitlist (RCT)

6

31, 35.5%

NR

Indigenous Australian adults with past-2-week suicidal thoughts

• No between-group differences in SI, impulsivity

• ↓ in depression and distress in app group > waitlist

6.45% (2)

  1. BPD Borderline personality disorder; DBT Dialectical behavior therapy, NR Not reported, NSSI Nonsuicidal self-injury, PTSD Post-traumatic stress disorder, RCT Randomized controlled trial, RELAX Remote Exercises for Learning Anger & Excitation Management, SI Suicidal ideation, SITB Self-injurious thoughts and behaviors, STAXI State-trait anger expression inventory, SUD Substance use disorder, TAU Treatment as usual, VHB Virtual Hope Box
  2. a= standalone intervention
  3. b= data presentation not amenable to meta-analysis
  4. cComputed from received allocated intervention/accessed the smartphone application, from intervention condition
  5. ↓ = decrease
  6. ↑ = increase