Table 3 P-values and r-squared values (in parentheses) obtained from multi factorial ANOVA models of the effect of sex, ELS, and 5-HTTLPR genotype on SLC6A4 methylation
From: New-born females show higher stress- and genotype-independent methylation of SLC6A4 than males
| Â | CpG site | ||||
|---|---|---|---|---|---|
Predictor in model | 1 | 2 | 3 | 4 | Mean across sites |
Sex | 3.9e-08 (0.302) | 2.3e-09 (0.361) | 1.2e-07 (0.288) | 3.7e-08 (0.311) | 7.5e-10 (0.371) |
ELS | 0.94 (0.000) | 0.67 (0.004) | 0.92 (0.001) | 0.96 (0.000) | 0.94 (0.001) |
Genotype | 0.12 (0.070) | 0.47 (0.028) | 0.95 (0.005) | 0.72 (0.027) | 0.75 (0.025) |
Sex x ELS | 0.76 (0.001) | 0.33 (0.006) | 0.78 (0.003) | 0.56 (0.003) | 0.63 (0.002) |
Sex x Genotype | 0.50 (0.011) | 0.61 (0.008) | 0.73 (0.004) | 0.51 (0.011) | 0.57 (0.008) |
ELS x Genotype | 0.79 (0.003) | 0.41 (0.013) | 0.44 (0.012) | 0.74 (0.005) | 0.52 (0.009) |