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Table 2 Psychopathology and socioeconomic-, psychosocial-, and perceived stress of the extreme group mothers (all data: mean ± SD or percentage)

From: New-born females show higher stress- and genotype-independent methylation of SLC6A4 than males

Variable High prenatal ELS (n = 45) Low prenatal ELS (n = 45) p value
Maternal psychopathology    
EPDS Score1 12.33 ± 4.70 1.27 ± 1.45 0.000
STAI-S Score1 51.72 ± 8.05 27.41 ± 3.87 0.000
STAI-T Score1 47.93 ± 8.41 28.04 ± 3.58 0.000
ASQ Score1 4.11 ± 2.14 0.53 ± 0.72 0.000
M.I.N.I. Diagnosis2    
   None 51.1% 91.1% 0.004
   Depressive disorder 40% 6.7% 0.015
   Anxiety disorder 8.9% 2.2% ns
Current psychiatric disorder2    
   None 62.2% 97.8% 0.005
   Depressive disorder 26.7% 0% 0.015
   Anxiety disorder 11% 2.2% ns
Perceived stress    
PSS Score1 30.84 ± 5.64 12.84 ± 4.1 0.000
PDQ Score1 19.95 ± 7.56 5.95 ± 2.95 0.000
Socioeconomic and psychosocial stress    
LES-negative events Score1 6.75 ± 4.39 1.80 ± 1.29 0.010
Soz-U Score1 39.58 ± 3.85 51.89 ± 4.32 0.000
Living without a partner2 20% 0% 0.004
Encouragement (Partner)2 73.3% 100% ns
Separation(s) in the last year2 24.4% 2.2% 0.002
Daily arguments2 11.1% 2.2% ns
Physical conflicts within the preceding 12 months2 33.3% 2.2% 0.003
Composition of household > one person/room2 40.5% 0% 0.001
No academic qualification2 4.4% 2.2% 0.050
No professional education2 17.7% 2.2% 0.043
Monthly income per household ≤ 1,750 Euro2 42.2% 0% 0.001
Debt2 24.4% 2.2% 0.002
  1. SD = standard deviation; ns = not significant. 1The first eight main variables of the principal component analysis (PCA), 2The twelve prenatal stressors used to generate the adversity score as the ninth main variable of the PCA.