New-born females show higher stress- and genotype-independent methylation of SLC6A4 than males

Table 1 Phenotypic assessment of mothers and infants at two time points

	Prenatal/3 ^rd trimester	Perinatal/birth
*Exposure to ELS*	Perceived stress (PSS) [33]	Pre- and perinatal complications
	Prenatal distress (PDQ) [34]	Perinatal stressors (e.g., asphyxia, cesarian, preterm birth)
	Life events (LES) [35]	Pregnancy & obstetric history (birth weight, gestational age, birth complications)
	Social support (Soz-U.) [36]
	Socio-demographic data
	Maternal health risk behavior (e.g. smoking)
	Psychosocial risks
*Maternal mental & physical health*	Maternity log-book data
	Semi-standardized neuropsychiatric diagnostic interview (MINI) [37]
	Depression screening (EPDS) [38]
	Anxiety screening (STAI-S [39], STAI-T [39], ASQ [40])
	Anthropometry
	Individual & family history of metabolic and other medical disorders

ELS = early life stress; PSS = perceived stress scale; PDQ = prenatal distress questionnaire; LES = life experiences survey; Soz-U = social support questionnaire; M.I.N.I. = Mini-international neuropsychiatric interview; EPDS = Edinburgh postnatal depression scale; STAI-S & STAI-T = state-trait anxiety inventory; ASQ = anxiety screening questionnaire.

ISSN: 2051-6673