|
Baehne et al. [21]
|
124 patients
|
Go/NoGo task (CPT)
|
TPH2 (G-allele polymorphism in rs4570625, T-allele polymorphism in rs11178997)
|
EEG (NGA)
|
Reduced NGA in risk allele carriers in ADHD and healthy controls
|
|
84 controls
|
|
Dresler et al. [24]
|
161 patients
|
Go/NoGo task (CPT)
|
SLC6A3 (3′ UTR VNTR)
|
EEG (NGA)
|
Reduced NGA in 9-repeat allele carriers in the patients, no influence in healthy controls
|
|
109 controls
|
|
Fallgatter et al. [29]
|
216 patients
|
Go/NoGo task (CPT)
|
LPHN3
|
EEG (NGA)
|
Reduced NGA in the LPHN3 high risk group
|
|
Heinzel et al. [25]
|
181 patients
|
Go/NoGo task (CPT)
|
COMT (Val158Met), DRD4 (exon 3 VNTR)
|
EEG (NGA)
|
Significant DRD4 × COMT interaction on NGA (DRD4 no7R: inverted u-shape with increasing COMT-dependent DA levels, DRD4 7R: u-shape), no gene main effects, no interaction with group
|
|
114 controls
|
|
Brown et al. [23]
|
52 patients
|
Working memory (n-back)
|
SLC6A3 (3′ UTR VNTR)
|
fMRI
|
Marginal reduced left mePFC signal in 9-repeat allele carriers in patients and controls, marginal genotype-by-diagnosis interaction in the SMA/dACC (increased activation in 10-repeat allele homozygous patients vs. controls)
|
|
38 controls
|
|
Brown et al. [30]
|
42 patients
|
Multi-source interference task
|
SLC6A3 (3′ UTR VNTR)
|
fMRI
|
Hypoactivation in 9-repeat allele homozygous patients in the left dACC
|
|
Hoogman et al. [32]
|
63 patients
|
Delay discounting task
|
NOS1 exon 1f-VNTR
|
fMRI
|
SS-allele carriers demonstrate higher ventral striatum activity in patients
|
|
41 controls
|
|
Hoogman et al. [34]
|
87 patients
|
Delay discounting task
|
SLC6A3 (3′UTR VNTR/intron 8 VNTR haplotype)
|
fMRI
|
No significant effects of DAT1 haplotype on striatal activity
|
|
77 controls
|
